Aplicación de ácido tranexámico para la reducción del sangrado perioperatorio en la cirugía estética corporal

Authors

  • Juan José Fuentes-Alzate Universidad Javeriana. Facultad de Medicina. Bogotá D.C, Colombia. https://orcid.org/0000-0001-5384-271X
  • Edgard Augusto Fuentes-Torrado Universidad del Bosque y Universidad de la Sabana. Facultad de Medicina. Bogotá D.C, Colombia.
  • Juan Pablo Alzate-Granados Universidad Nacional. Facultad de Medicina. Bogotá D.C, Colombia.

Keywords:

Abdominoplasty, Hemorrhage, Liposuction, Tranexamic acid.

Abstract

Introduction: liposuction and tummy tuck are two of the most performed body contouring surgeries in the world. These procedures are so common that it is important to know the risks associated with them. Bleeding complications are the second cause of fatal outcomes in this type of cosmetic intervention, after pulmonary thromboembolism. Taking into account the prevalence of this entity, we consider that new methods should be sought to reduce blood loss in this type of surgery. Against this background, the possibility of using tranexamic acid has arisen because it prevents the degradation of the blood clot, thus reducing perioperative bleeding.

Objective: to describe the results of the use of tranexamic acid in patients undergoing abdominoplasty and liposuction.

Method: an observational prospective cohort study was proposed in a group of 37 female patients who were administered tranexamic acid during anesthetic induction to perform abdominoplasty plus body liposuction at the clinic “Santa Barbara Surgical Center” in the city of Bogotá, Colombia. In these patients, a pre-surgical and a post-surgical hemogram was reviewed and the hemoglobin and hematocrit was compared. Likewise, it was reviewed whether the patients had the need for blood component transfusion.

Results: a Spearman correlation was performed between the variables, in which no association was evidenced between the lipoaspirate and the postoperative hemoglobin or hematocrit. None of the patients presented a postsurgical hemoglobin less than 8 g / dl or required transfusion of blood products after surgery. None of the patients had thromboembolic complications after the procedure.

Conclusions: the tranexamic acid is a drug that can be useful for reducing perioperative blood perioperative blood loss in liposuction and abdominoplasty, because none of the patients involved in the required transfusion of red blood cells.

References

1. International Society of Aesthetic Plastic Surgery. ISAPS International Survey on Aesthetic / Cosmetic Procedures Performed in 2018. International Society of Aesthetic Plastic Surgery [Internet]. 2019 [citado 21/08/2021]; Disponible en: https://www.isaps.org/wp-content/uploads/2019/12/ISAPS-Global-Survey-Results-2018-new.pdf

2. Dixit VV, Wagh MS. Unfavourable outcomes of liposuction and their management. Indian J Plast Surg. [Internet]. 2013 [citado 21/08/2021]; 46(2):377. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901919/

3. Samdal F, Amland PF, Bugge JF. Blood loss during liposuction using the tumescent technique. Aesthetic Plast Surg. [Internet]. 1994 [citado 21/08/2021]; 18(2):157–60. Disponible en: https://pubmed.ncbi.nlm.nih.gov/8017219/

4. Venkataram J. Chapter-16 microcannular tumescent liposuction. Dermatologic Surgery Made Easy. [Internet]. 2012 [citado 21/08/2021]; 195–212.

5. Consanção AL, Condé-Green A, David JA, Cansancao B, Vidigal RA. Use of tranexamic acid to reduce blood loss in Liposuction. Plast Reconstr Surg. [Internet]. 2018 [citado 21/08/2021]; 141(5):1132–5. Disponible en: https://pubmed.ncbi.nlm.nih.gov/29697607/

6. Ministerio de Salud de Colombia. Resolución número RESOLUCIÓN 8430 de 1993 [Internet]. 1993 [citado 21/08/2021]. Disponible en: https://www.minsalud.gov.co/sites/rid/Lists/BibliotecaDigital/RIDE/DE/DIJ/RESOLUCION-8430-DE-1993.PDF

7. Oliver JD, DeLoughery EP, Gupta N, Boczar D, Sisti A, Huayllani MT, et al. Local pro- and anti-coagulation therapy in the plastic surgical patient: A literature review of the evidence and clinical applications. Medicina (Kaunas) [Internet]. 2019 [citado 21/08/2021]; 55(5):208. Disponible en: https://pubmed.ncbi.nlm.nih.gov/31137735

8. Ghavimi MA, Taheri Talesh K, Ghoreishizadeh A, Chavoshzadeh MA, Zarandi A. Efficacy of tranexamic acid on side effects of rhinoplasty: A randomized double-blind study. J Cranio-Maxillofacial Surg. [Internet]. 2017 [citado 21/08/2021]; 45(6):897-902. Disponible en: http://dx.doi.org/10.1016/j.jcms.2017.03.001

9. Murphy GR, Glass GE, Jain A. The efficacy and safety of tranexamic acid in Cranio-Maxillofacial and plastic surgery. J Craniofac Surg. [Internet]. 2016 [citado 21/08/2021]; 27(2):374-9. Disponible en: https://pubmed.ncbi.nlm.nih.gov/26967076/

10. Rohrich RJ, Cho M-J. The role of tranexamic acid in plastic surgery. Plast Reconstr Surg. [Internet]. 2018 [citado 21/08/2021]; 141(2):507-15. Disponible en: https://pubmed.ncbi.nlm.nih.gov/28938364/

11. Coleman WP, Coleman K. Tumescent liposuction. Practical Dermatologic Surgery. [Internet]. 2021 [citado 21/08/2021]; 193–8.

12. Nayak LM, Linkov G. The role of tranexamic acid in plastic surgery. Plast Reconstr Surg. [Internet]. 2018 [citado 21/08/2021]; 142(3). Disponible en: https://pubmed.ncbi.nlm.nih.gov/29965923/

13. Elena Scarafoni E. A systematic review of tranexamic acid in plastic surgery: What’s new? Plast Reconstr Surg Glob Open. [Internet]. 2021 [citado 21/08/2021];9(3). Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062149/

14. Sood J, Sethi N, Jayaraman L. Liposuction: Anaesthesia challenges. Indian J Anaesth [Internet]. 2011 [citado 21/08/2021]; 55(3):220. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141144/

15. Brown S, Brown T, Tessone A. The role of tranexamic acid in Rhinoplasty. Plast Reconstr Surg Glob Open [Internet]. 2020 [citado 21/08/2021]; 8(9S):5–6. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553392/

16. Locketz GD, Lozada KN, Bloom JD. Tranexamic acid in aesthetic FACIAL PLASTIC SURGERY: A systematic review of Evidence, applications, and outcomes. Aesthet Surg J Open Forum. [Internet]. 2020 [citado 2021Ago18]; 2(3). Disponible en: https://pubmed.ncbi.nlm.nih.gov/33791652/

17. Fu R, Liu C, Yan Y, Suo L, Xie Y, Li Q, et al. Tranexamic acid in CRANIOMAXILLOFACIAL SURGERY: A meta-analysis and systematic review. Facial Plast Surg Aesthet Med. [Internet]. 2021 [citado 21/08/2021]. Disponible en: https://pubmed.ncbi.nlm.nih.gov/33661026/

Published

2021-12-16

How to Cite

1.
Fuentes-Alzate JJ, Fuentes-Torrado EA, Alzate-Granados JP. Aplicación de ácido tranexámico para la reducción del sangrado perioperatorio en la cirugía estética corporal. Rev 16 de abril [Internet]. 2021 Dec. 16 [cited 2025 Feb. 23];60(282):e1405. Available from: https://rev16deabril.sld.cu/index.php/16_04/article/view/1405

Issue

Section

Original Articles