Environmental risk factors associated with the appearance of neoplasms of the digestive system

Authors

  • Susana Pérez-González Universidad de Ciencias Médicas de Pinar del Río. Facultad de Ciencias Médicas “Dr. Ernesto Guevara de la Serna”. Pinar del Rio, Cuba. https://orcid.org/0000-0001-8646-9210
  • Eduardo Enrique Cecilia-Paredes Universidad de Ciencias Médicas de Pinar del Río. Facultad de Ciencias Médicas “Dr. Ernesto Guevara de la Serna”. Pinar del Rio, Cuba. https://orcid.org/0000-0002-0613-5075
  • Arainé Santalla-Corrales Universidad de Ciencias Médicas de Pinar del Río. Facultad de Ciencias Médicas “Dr. Ernesto Guevara de la Serna”. Pinar del Rio, Cuba. https://orcid.org/0000-0003-1543-3848
  • Elizabeth Cecilia-Paredes Universidad de Ciencias Médicas de Pinar del Río. Facultad de Ciencias Médicas “Dr. Ernesto Guevara de la Serna”. Pinar del Rio, Cuba. https://orcid.org/0000-0001-8423-432X
  • Víctor Livan Cabrera-Martínez Universidad de Ciencias Médicas de Pinar del Río. Facultad de Ciencias Médicas “Dr. Ernesto Guevara de la Serna”. Pinar del Rio, Cuba. https://orcid.org/0000-0002-9462-5858
  • Eliza Maritza Linares-Guerra Universidad “Hermanos Saiz Monte de Oca”. Facultad de Ciencias Técnica. Pinar del Río, Cuba. https://orcid.org/0000-0002-6333-867X

Keywords:

Cancer, Risk Factors, Environment, Digestive System.

Abstract

Introduction: cancer is a disease of multifactorial origin that develops after long periods of latency. Current trends in cancer of the digestive system, specifically, have been affected as a result of many factors, including environmental ones.

Objective: to characterize the environmental risk factors associated with the appearance of neoplasms of the digestive system in patients treated at III Congreso Oncology Hospital in Pinar del Río province.

Method: an observational, descriptive and cross-sectional study was carried out in the period September-December 2019. The population consisted of 184 individuals and was studied in its entirety. The analysis performed was descriptive.

Results: the most affected age group was 51 to 60 years old (n = 60; 32.6%) and the predominant sex was male (n = 108; 58.7%). A predominance of intestinal cancer was found (n = 95; 51.6%), specifically colon cancer (n = 66; 70%). Sedentary lifestyle turned out to be the most represented risk factor. A moderate statistical association (p < 0.05; 0.2 ≤ V < 0.4) was established between the risk factors (frequent soy consumption and sedentary lifestyle) and the anatomical location of the tumor.

Conclusions: a sedentary lifestyle and frequent consumption of soy were the main risk factors for the development of neoplasms of the digestive system. The first two factors were associated with the anatomical location of the tumor.

References

1. Marks AD, Lieberman M, Peet A. The molecular biology of cancer. En: Marks Basic Medical Biochemistry a Clinical Approach. 6ta ed. Filadelfia: Lippincott Williams & Wilkins; 2022. pp. 759-812.

2. Bermúdez Garcell AJ, Serrano Gámez NB, Teruel Ginés R, Leyva Montero MÁ, Naranjo Coronel AA. Biología del cáncer. ccm [Internet]. 2019 [citado 03/09/2022]; 23(4):1394-1416. Disponible en: http://www.revcocmed.sld.cu/index.php/cocmed/article/view/3350/1708

3. Abdo Francis JM. Cáncer del aparato digestivo. Rev Med del Hospital General de México [Internet]. 2016 [citado 02/09/2022]; 73(1):7–8. Disponible en: https://www.medigraphic.com/pdfs/h-gral/hg-2010/hg101b.pdf

4. World Health Organization. Latest global cancer data: Cancer burden rises to 18.1 million new cases and 9.6 million cancer deaths in 2019 [Internet]. 2018 [citado 02/09/2022]. Disponible en: https://www.iarc.who.int/featured-news/latest-global-cancer-data-cancer-burden-rises-to-18-1-million-new-cases-and-9-6-million-cancer-deaths-in-2019/

5. Organización Panamericana de la Salud. Cáncer [Internet]. 2019. [citado 02/09/2022]. Disponible en: https://www.who.int/es/news-room/fact-sheets/detail/cáncer

6. Parra-Soto S, Petermann-Rocha F, Martínez-Sanguinetti MA, Leiva-Ordeñez AM, Troncoso-Pantoja C, Ulloa N, et al. Cáncer en Chile y en el mundo: una mirada actual y su futuro escenario epidemiológico. Rev méd Chile [Internet]. 2020 [citado 03/09/2022]; 148(10):1489-1495. Disponible en: http://dx.doi.org/10.4067/S0034-98872020001001489.

7. Ríos JA, Barake FM, Arce MJ, López-Köstner F, Labbe TP, Villena J, Becerra S. Situación actual del cáncer de colon en Chile: una mirada traslacional. Rev Med Chile [Internet]. 2020 [citado 02/09/2022]; 148(1):858-867. Disponible en: https://scielo.conicyt.cl/pdf/rmc/v148n6/0717-6163-rmc-148-06-0858.pdf

8. MINSAP. Dirección de Registros Médicos y Estadísticas de Salud. Anuario Estadístico de Salud 2018. La Habana: 2019 [citado 18/09/2022]. Disponible en: https://files.sld.cu/bvscuba/files/2019/04/Anuario-Electrónico-Español-2018-ed-2019-compressed.pdf

9. MINSAP. Dirección de Registros Médicos y Estadísticas de Salud. Anuario Estadístico de Salud 2019. La Habana: 2020 [citado 18/09/2022]. Disponible en: https://files.sld.cu/bvscuba/files/2020/05/Anuario-Electrónico-Español-2019-ed-2020.pdf

10. MINSAP. Dirección de Registros Médicos y Estadísticas de Salud. Anuario Estadístico de Salud 2020. La Habana: 2021 [citado 18/09/2022]. Disponible en: https://salud.msp.gob.cu/wp-content/Anuario/Anuario-2020.pdf

11. Rubín-García M, Martín V, Vitelli-Storelli F, Moreno V, Aragonés N, Ardanaz E et al. Antecedentes familiares de primer grado como factor de riesgo en el cáncer colorrectal. Gaceta Sanitaria [Internet]. 2022 [citado 02/09/2022]; 36(4):345-352. Disponible en: https://www.gacetasanitaria.org/en-antecedentes-familiares-primer-grado-como-articulo-S0213911121001096

12. Trujillo-Pérez YL, Rojas-Peláez Y, Carmenates-Álvarez BM, Reyes-Escobar AD, Pérez-Álvarez M. Comportamiento del cáncer colorrectal en el Hospital Provincial Clínico Quirúrgico Docente Amalia Simoni. Rev Arch Med Camagüey [Internet]. 2019 [citado 02/09/2022];23(2):188-197. Disponible en: http://www.revistaamc.sld.cu/index.php/amc/article/view/6269

13. Utrera-Díaz G, Pérez-Rodríguez L, Toledo-Yanes P. Cáncer colorrectal: factores de riesgo en pacientes mayores de 50 años en Cienfuegos. Revista Finlay [Internet]. 2021 [citado 03/09/2022];11(3):[aprox. 6 p.]. Disponible en: http://www.revfinlay.sld.cu/index.php/finlay/article/view/920

14. Valdés-Villafranca R, Pérez-García S, Ramos-Cordero Á, Pérez-García S, Valdés-Villafranca R, Hernández E. Mortalidad prematura por cáncer colorrectal. Revista Finlay [revista en Internet]. 2020 [citado 03/09/2022];10(4):[aprox. 8 p.]. Disponible en: http://www.revfinlay.sld.cu/index.php/finlay/article/view/889

15. González L, Estepa JL, Feliú JA, Santana T, Estepa JL. Caracterización de pacientes operados de cáncer colorrectal. Cienfuegos, 2014 a 2016. Medisur [Internet]. 2018 [citado 02/09/2022];16(4):[aprox. 15 p.]. Disponible en: http://medisur.sld.cu/index.php/medisur/article/view/4048/2639

16. Cruz DF, Rojas A, Bastidas BE, Orozco-Chamorro CM. Cáncer del tubo digestivo en pacientes jóvenes del departamento del Cauca, tipificación clínica. Rev colomb cir [Internet]. 2019 [citado 03/09/2022];34(2):153-162. Disponible en: https://www.revistacirugia.org/index.php/cirugia/article/view/109

17. Muñoz-Cedeño R, Martínez P, Paullán-Sani V, Rodríguez-Chica G. Caracterización clínica, histológica y endoscópica del cáncer gástrico en el Hospital de Especialidades Dr. Abel Gilbert Pontón, Ecuador. Rev Colomb Gastroenterol. [Internet]. 2021 [citado 03/09/2022];36(1):163-171. Disponible en: https://revistagastrocol.com/index.php/rcg/article/view/558

18. Lu PY, Shu L, Shen SS, Chen XJ, Zhang XY. Dietary Patterns and Pancreatic Cancer Risk: A Meta-Analysis. Nutrients Rev [Internet]. 2020 [citado 02/09/2022]; 9(1):38. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295082/

19. Shin A, Lee J, Lee J, Park MS, Park JW, Park SC, et al. Isoflavone and Soyfood Intake and Colorectal Cancer Risk: A Case-Control Study in Korea. PLoSOne [Internet]. 2018 [citado 02/09/2022];10(11):e0143228. Disponible en: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0143228

20. Niaz K, Maqbool F, Khan F, Bahadar H, Hassan FI, Abdollahi M. Smokeless tobacco (paan and gutkha) consumption, prevalence, and contribution to oral cancer. Epidemiol Health [Internet]. 2019 [citado 02/09/2022]; 39:e2017009. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543298/

21. Ma P, Yao Y, Sun W, Zhou C. Daily sedentary time and its association with risk for colorectal cancer in adults. Medicine (Baltimore) [Internet]. 2018 [citado citado 02/09/2022]; 96(22):e7049. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459729/

22. Keum N, Cao Y, Oh H, Smith-Warner SA, Orav J, Wu K, et al.Sedentary behaviors and light-intensity activities in relation to colorectal cancer risk. Int J Cancer [Internet]. 2019 [citado citado 02/09/2022]; 138(1):2109–2117. Disponible en: https://koreauniv.pure.elsevier.com/en/publications/sedentary-behaviors-and-light-intensity-activities-in-relation-to

23. Wada K, Oba S, Tsuji M, Tamura T, Konishi K, Goto Y, et al. Meat consumption and colorectal cancer risk in Japan: The Takayama study. Cancer Sci [Internet]. 2018 [citado 02/09/2022]; 108(5):1065–1070. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448603/

Downloads

Published

2022-10-16

How to Cite

1.
Pérez-González S, Cecilia-Paredes EE, Santalla-Corrales A, Cecilia-Paredes E, Cabrera-Martínez VL, Linares-Guerra EM. Environmental risk factors associated with the appearance of neoplasms of the digestive system. Rev 16 de abril [Internet]. 2022 Oct. 16 [cited 2025 Mar. 12];61(285):e1711. Available from: https://rev16deabril.sld.cu/index.php/16_04/article/view/1711

Issue

Vol. 61 No. 285 (2022): Julio-Septiembre

Section

Original Articles

License

Those authors who have publications with this journal, accept the following terms:

The authors will retain their copyright and guarantee the journal the right of first publication of your work, which will be under a Creative license Commons Attribution-NonCommercial-ShareAlike 4.0 International . (CC BY-NC-SA 4.0).

The authors may adopt other non-exclusive license agreements for the distribution of the published version of the work (eg:deposit it in an institutional telemat